Monday, September 3, 2012

Osteoporosis - Facts About Disease, prevention And treatment Women Should Know

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Current statistics state that osteoporosis affects 10 million Americans and 8 million women, or 55% of population over 50 are thinkable, to be affected by osteoporosis. 1 in 2 women are thinkable, to have an osteoporosis connected fracture in their lifetime. This is a critical cause of morbidity as hip and spine fractures cause serious impairment of mobility and health concerns connected to immobility. There is much in the news about medications and recommended supplements to take, as well as life style changes to help combat osteoporosis. Comprehension the disease process helps to understand how these different treatments impact bone density, thereby enabling women to make informed decisions regarding their rehabilitation of osteoporosis and osteopenia.

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The majority of bone density, up to 90%, is formed by age 18 in women and age 20 in men. There are two types of cells which form and mouth salutary bone, osteoblasts are responsible for laying down salutary bone matrix which then undergoes mineralization with the aid of calcium, which adds strength. Osteoclasts are cells which are responsible for resorbing older bone, in so doing, the osteoclasts ensure that remaining bone is strong. In the early years of our lives, the action of osteoblasts are balanced with osteoclasts. In osteoporosis, the osteoblasts have slowed in their formation of bone, any way resorption of bone has continued at its usual rate. Because of this imbalance, bone gently thins placing a woman at risk of a break or fracture. A number of factors can sway the balance and imbalance of this process:

Parathyroid hormone

Vitamin D metabolites

Prostaglandins

Cortisol

Sex hormones

Osteoporosis is a term referring to loss of bone density to the extent that a fracture is possible, osteopenia is a term reflecting a degree of bone loss not severe sufficient to place a man at risk for a fracture. A person's bone density is carefully most accurately by a test, Bone Mineral Density test. The most strict of these types of tests is the Central Dxa, or dual power x-ray absorptiometry. In this test, the bone density is calculated, and then compared to women of same age and height to conclude if there is a process also aging causing increased bone loss. This calculated density is also compared to women of same height at 30 years of age, and then the calculated unlikeness of bone density determines the degree of bone density loss.

Who is at risk for osteoporosis and osteopenia?
• Women with decreased estrogen ie. Postmenopausal women, premature ovarian failure
• Women undergoing chemotherapy for breast cancer, use of aromatase inhibitors
• Women who have been on continued use of depo-Provera
• Women and men who have been on steroids for long periods of time, anticonvulsants. Lithium,heparin
• poor dietary intake of calcium and vitamin D
• inactive and sedentary people
• People of Caucasian, Asian and Latino more so than Aftrican American ethnicities
• Smokers
• People who use of alcohol excessively (>3/day)
• people with clear forms of arthritis and gastrointestinal illnesses

Treatment for osteoporosis is usually in case,granted in the form of bisphosphonate therapy. These drugs, the bis-phosphonates (Fosomax and others) work by slowing the action of osteoclasts in bone. Other rehabilitation includes estrogen which attenuates the resorption of bone or the osteoclast activity. Calcitonin is a thyroid derived peptide which also inhibits osteoclast activity. This form of rehabilitation has not been shown to be as sufficient in preventing vertebral fractures.

The bisphosphonates are a very sufficient rehabilitation in helping to furnish new bone, although it has been recently speculated that this bone may not be as salutary as natural bone. For women that have sufficient bone loss to place them at serious risk for a fracture however, this bis-phosphonate induced bone can be protective to some extent. In recent studies by Orthopedic Surgeons, it was noted that bone integrity was improved early on in therapy but that benefit was lost after more than 4 years of treatment. As with many things in medicine, there are risks and benefits to be weighed when inspecting osteoporosis medication. It is prominent to discuss this with you provider before stopping any medication.

Life style changes are equally prominent in preventing and treating osteoporosis and osteopenia.
Exercise and diet also play an prominent role in preventing and treating osteoporosis.

• Muscle building rehearsal helps to activate the osteoblasts to lay down new bone,
• Calcium in our diet helps to make that bone strong, and
• Vitamin D helps our body to suck in and process the calcium.

Muscle building rehearsal of 90 minutes a week is recommended for bone health. An increased rehearsal time of 150 minutes a week is recommended for heart health and to lower insulin resistance. This muscle building rehearsal does not have to be high impact; brisk walking is perfect but as far as we know now, swimming will not help your bones as it is not weight bearing.

Calcium supplements will suffice to replace or augment dairy products. 1200-1500 mg of calcium daily is the recommended dose for post menopausal women. There are some different types of supplements and they are all good but are tolerated differently, experimentation will yield the best tolerated brand for any given person.

Vitamin D3 capsules or pills are recommended as it is difficult to get sufficient Vitamin D in the diet. Vitamin D3, or ergocalciferol, is the recommended type as this last longer in the body. It is prominent to get a brand that does not consist of Vitamin A as the body cannot regulate this precisely and toxicity as well as overdose is possible.

Osteoporosis is a silent but serious disease which can be precisely prevented and treated. Screening is painless and usually covered by insurance clubs if medically indicated. It is prominent for women to advent their medical providers for screening and data for both themselves and for male partners who may also be at risk.

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